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One of the major challenges encountered is the heterogeneity in study design, sample size, population characteristics, and dosage and duration of supplementation

J Chem Neuroanat 80:110 Yan X et al (2017) Vanillin protects dopaminergic neurons against inflammation-mediated cell death by inhibiting ERK1/2, P38 and the NF-B signaling pathway

Analysis suggested GHK Cu upregulates genes associated with tissue repair, collagen production, and anti-aging biology, while downregulating genes associated with inflammation, cancer progression, and oxidative stress (Pickart and Margolina, Biomedicines, 2018)